Phenotypes Associated with This Genotype

Genotype
MGI:3714496

• Allelic Composition: Nkd1^tm1Kwha/Nkd1^tm1Kwha
• Genetic Background: involves: 129S/SvEv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

short nasal bone ( J:122353 )

• Background Sensitivity: nasal bones are slightly shortened relative to controls or homozygotes on the mixed background

postnatal growth retardation ( J:122353 )

• Background Sensitivity: 4- to 12-week old pups fed ad libitum show a slight but significant growth retardation (15% in males at 12 weeks, 4.6% in females at 12 weeks) compared to wild-type mice

reproductive system

reproductive system phenotype ( J:122353 )

N • Background Sensitivity: mice are viable and fertile; average litter size is 7.3

N • 3-month old males had similar testis-to-body weight as controls and normal spermatogenesis

craniofacial

short nasal bone ( J:122353 )

• Background Sensitivity: nasal bones are slightly shortened relative to controls or homozygotes on the mixed background

skeleton

short nasal bone ( J:122353 )

• Background Sensitivity: nasal bones are slightly shortened relative to controls or homozygotes on the mixed background

respiratory system

short nasal bone ( J:122353 )

• Background Sensitivity: nasal bones are slightly shortened relative to controls or homozygotes on the mixed background