Mouse Genome Informatics
cn
    Erbb2tm8(Erbb2)Mul/Erbb2+
Tg(MMTV-cre)7Mul/?

involves: 129S1/Sv * 129X1/SvJ * FVB/N
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
endocrine/exocrine glands
• numerous lobular side buds with acinar structures are observed (J:61202)
• mice develop precocious lobualveolar hyperplasias of the mammary glands (J:89255)

tumorigenesis
• virgin female mutants develop mammary tumors with an average latency of 15.9 months with >90% affected by 2 years of age

integument
• numerous lobular side buds with acinar structures are observed (J:61202)
• mice develop precocious lobualveolar hyperplasias of the mammary glands (J:89255)

Mouse Models of Human Disease
OMIM IDRef(s)
Breast Cancer 114480 J:167180