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Phenotypes Associated with This Genotype
Genotype
MGI:3714362
Allelic
Composition		 Stub1tm1Atak/Stub1tm1Atak
Genetic
Background		 B6.Cg-Stub1tm1Atak
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stub1tm1Atak mutation (0 available); any Stub1 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:100900 )
• 95% of mice die by week 3

growth/size/body
decreased body weight ( J:100900 )

behavior/neurological
ataxia ( J:100900 )
• mice cannot coordinate walking due to nervous lesions (dysbasia)

nervous system
tau protein deposits ( J:100900 )
• increased levels of tau are observed in brains of aged mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory