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Phenotypes Associated with This Genotype
Genotype
MGI:3713865
Allelic
Composition		 Smad2m1Mag/Smad2tm1Rob
Genetic
Background		 either: (involves: 129S/Sv * 129S/SvEv * Black Swiss) or (involves: 129S/Sv * 129S/SvEv * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smad2m1Mag mutation (0 available); any Smad2 mutation (50 available)
Smad2tm1Rob mutation (0 available); any Smad2 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:80520 )
• only empty yolk sacs are found at E11.5

embryo
abnormal embryonic tissue morphology ( J:80520 )
• at E11.5, no embryonic portion is present in highly developed yolk sac

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory