About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3713804
Allelic
Composition		 Rbpjtm1Hon/Rbpjtm1Hon
Tg(Pax2-cre)1Akg/0
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rbpjtm1Hon mutation (2 available); any Rbpj mutation (191 available)
Tg(Pax2-cre)1Akg mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:119907 )
• embryos are normal at E12.5, but die at E13.5

renal/urinary system
absent podocytes ( J:119907 )
• podocytes with WT1high expression do not develop in E12.5 cultures
abnormal proximal convoluted tubule morphology ( J:119907 )
• cultured E12.5 mtanephroi branch normally, but tubules positive for LTL (lectin) are not detected

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory