Analysis Tools
digestive/alimentary system
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• less colon shortening
• decreased leukocyte infiltration
• less crypt loss
• reduced epithelial hyperplasia
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immune system
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• less colon shortening
• decreased leukocyte infiltration
• less crypt loss
• reduced epithelial hyperplasia
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• 15 days after aerosol challenge with M. tuberculosis, mice produce less CD4+ T cells with an activated CD44hiCXCR3+ phenotype than wild-type
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• following vaccination against M. tuberculosis, mice do not lower bacterial burden in the lung 30 days after challenge and fail to elicit an accelerated IFN-gamma or IL-17 T cell recall response
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• low levels of IL22 after DSS treatment
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• increase in levels after DSS treatment is less than for controls
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• 15 days after aerosol challenge with M. tuberculosis, mice fail to produce mononuclear granulomatous structures as wild-type mice do
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• following vaccination against M. tuberculosis, mice do not lower bacterial burden in the lung 30 days after challenge and fail to elicit an accelerated IFN-gamma or IL-17 T cell recall response
• 15 days after aerosol challenge with M. tuberculosis, mice fail to produce mononuclear granulomatous structures as wild-type mice do
• 15 days after aerosol challenge with M. tuberculosis, mice produce less CD4+ T cells with an activated CD44hiCXCR3+ phenotype than wild-type mice
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hematopoietic system
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• 15 days after aerosol challenge with M. tuberculosis, mice produce less CD4+ T cells with an activated CD44hiCXCR3+ phenotype than wild-type
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• following vaccination against M. tuberculosis, mice do not lower bacterial burden in the lung 30 days after challenge and fail to elicit an accelerated IFN-gamma or IL-17 T cell recall response
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homeostasis/metabolism
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• low levels of IL22 after DSS treatment
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• increase in levels after DSS treatment is less than for controls
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• significantly less weight loss after treatment with Sodium Dextran Sulfate (DSS) than in controls
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