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Phenotypes Associated with This Genotype
Genotype
MGI:3712956
Allelic
Composition		 Cdk4tm1Kiyo/Cdk4+
Lin9tm1Orc/Lin9+
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdk4tm1Kiyo mutation (0 available); any Cdk4 mutation (57 available)
Lin9tm1Orc mutation (0 available); any Lin9 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell cycle ( J:111333 )
• number of MEF cells in S-phase is increased by 2.3-fold

immune system
decreased susceptibility to autoimmune diabetes ( J:111333 )
• mice do not develop early onset diabetes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory