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Phenotypes Associated with This Genotype
Genotype
MGI:3712790
Allelic
Composition		 Tsc2tm1Mjg/Tsc2+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tsc2tm1Mjg mutation (0 available); any Tsc2 mutation (78 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
kidney cyst ( J:121748 )
• heterozygotes develop renal cysts after 1 year of age, but no renal tumors were identified like in reports for homozygous nulls by 1 year of age

growth/size/body
kidney cyst ( J:121748 )
• heterozygotes develop renal cysts after 1 year of age, but no renal tumors were identified like in reports for homozygous nulls by 1 year of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory