Analysis Tools
reproductive system
 N |
• homozygous females are viable and fertile
|
homeostasis/metabolism
|
|
• thrombi formed in response to FeCl3 injury are fragile and prone to rupture and to embolizing
• smaller thrombi with lower platelet density
• clotting times are normal
|
immune system
microgliosis
(
J:115487
)
|
|
• increased microgliosis
|
|
|
• early onset of disease when infected with scrapie
• succumb to infection after 144 days as opposed to 184 days for controls
• symptoms of scrapie infection equivalent to 1000X higher dose
|
nervous system
microgliosis
(
J:115487
)
|
|
• increased microgliosis
|
|
|
• more severe loss of parvalbumin positive neurons in the cortex as a result of scrapie infection than occurs in controls
|
|
|
• increased apoptosis
|
|
|
• vacuolation resulting from scrapie infection more pronounced than in controls
|
hematopoietic system
microgliosis
(
J:115487
)
|
|
• increased microgliosis
|
cellular
microgliosis
(
J:115487
)
|
|
• increased microgliosis
|
