Phenotypes Associated with This Genotype

Genotype
MGI:3712294

• Allelic Composition: Lamtor2^tm1.2Lah/Lamtor2^tm1.2Lah
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:119075 )

• by E10.5, no homozygous embryos are detected

• homozygous embryos appear normal at E6.5, in size and number

embryo

embryonic growth retardation ( J:119075 )

• at E8.5, ~25% of embryos are growth retarded

abnormal embryonic tissue morphology ( J:119075 )

• at E8.5, ~25% of embryos show severe developmental defects

growth/size/body

embryonic growth retardation ( J:119075 )

• at E8.5, ~25% of embryos are growth retarded