Phenotypes Associated with This Genotype

Genotype
MGI:3711903

• Allelic Composition: Gli3^Xt/Gli3⁺
• Genetic Background: involves: 101/H * 129 * C3H/HeH * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

abnormal digit morphology ( J:121609 )

• digits have lost their identity with some digits consisting of three phalanges that are usually undivided and longer than those in Gli3^tm2Blnw homozygotes

abnormal phalanx morphology ( J:121609 )

• phalanges in some digits are undivided and longer than those in Gli3^tm2Blnw homozygotes

• rarely extra phalanges element branch from the metatarsals

• however, ossification occurs at most proximal and distal phalanges

polydactyly ( J:121609 )

• at E16.5, some mice have 6 to 8 digits that lacked identity

absent tibia ( J:121609 )

• at E16.5, in some mice

skeleton

abnormal phalanx morphology ( J:121609 )

• phalanges in some digits are undivided and longer than those in Gli3^tm2Blnw homozygotes

• rarely extra phalanges element branch from the metatarsals

• however, ossification occurs at most proximal and distal phalanges

absent tibia ( J:121609 )

• at E16.5, in some mice