Phenotypes Associated with This Genotype

Genotype
MGI:3711877

• Allelic Composition: Gas1^tm2Fan/Gas1^tm2Fan; Shh^tm1Chg/Shh⁺
• Genetic Background: involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

oligodactyly ( J:121554 )

• 16% of forelimbs have 4.5 digits, 84% of forelimbs and 100% of hindlimbs are missing digit 2

• no digit forms at the digit 2 position

nervous system

holoprosencephaly ( J:121554 )

• mild, with a narrowing and fusion of the midline facial structures

respiratory system

single external naris ( J:121554 )

• single nostril

craniofacial

single external naris ( J:121554 )

• single nostril

growth/size/body

single external naris ( J:121554 )

• single nostril