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Phenotypes Associated with This Genotype
Genotype
MGI:3711517
Allelic
Composition		 Pygo2tm1.1Ssp/Pygo2tm1.2Ssp
Tfap2atm1(cre)Moon/?
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pygo2tm1.1Ssp mutation (1 available); any Pygo2 mutation (24 available)
Pygo2tm1.2Ssp mutation (0 available); any Pygo2 mutation (24 available)
Tfap2atm1(cre)Moon mutation (1 available); any Tfap2a mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens induction ( J:121416 )
• at E9.5, lens induction is abnormal as indicated by reduced Pax6+ cells
small lens ( J:121416 )
• at E12.5, lens reduction is more severe than any other conditional cross but not as severe as in the Pygo2 null homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory