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Phenotypes Associated with This Genotype
Genotype
MGI:3710958
Allelic
Composition		 Ift88tm1Bky/Ift88tm1Bky
Tg(Col2a1-cre)1Bhr/?
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift88tm1Bky mutation (1 available); any Ift88 mutation (46 available)
Tg(Col2a1-cre)1Bhr mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
disproportionate dwarf ( J:121342 )
• at P30 dawrfism is observed
• however, at P0 mice appear normal

skeleton
abnormal long bone epiphyseal plate morphology ( J:121342 )
• at P15, growth plate structure is completely abrogated with ossification centers merged and the distance from the articular surface to the trabecular bone is reduced

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory