Mouse Genome Informatics
tg
    Tg(Prnp-ITM2B/APP695*40)1Emcg/0
involves: C3H * C57BL/6
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• mice do not show Abeta deposits or amyloid plaque formation

homeostasis/metabolism
• Abeta1-40 peptide levels in 3 month old transgenic brains are ~2- to 3-fold higher than levels in Tg(APPSWE)2576Kahs controls (80-120 pm/g vs ~40 pm/g)

Mouse Models of Human Disease
OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:101023