Mouse Genome Informatics
cn
    Brca1tm1Aash/Brca1tm1Aash
Tg(LGB-cre)74Acl/0

involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
tumorigenesis
• some mice (which have not gone through pregnancies) develop salivary gland myoepithelial tumors
• mammary tumors occur in these control mice at lower frequency (12%: 5/43 animals) and much longer latency (12-15 months) compared to mice on a Trp43-haploinsufficient background

Mouse Models of Human Disease
OMIM IDRef(s)
Breast Cancer 114480 J:119996