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Phenotypes Associated with This Genotype
Genotype
MGI:3710352
Allelic
Composition		 Xpctm1Ecf/Xpc+
Genetic
Background		 involves: 129 * SKH1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Xpctm1Ecf mutation (1 available); any Xpc mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
increased sensitivity to skin irradiation ( J:120007 )
• basal cells exhibit reduced levels of cyclobutane pyrimidine dimers (8.7% compared to 12% in wild-type mice) after a total UV dose of 1.0 kJ/m2
• however, no pyridine pirimidone photoproducts accumulate

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory