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Phenotypes Associated with This Genotype
Genotype
MGI:3710082
Allelic
Composition		 Ddb2tm1Vri/Ddb2+
Genetic
Background		 involves: 129P2/Ola * SKH1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ddb2tm1Vri mutation (0 available); any Ddb2 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased squamous cell carcinoma incidence ( J:103406 )
• 50% and 100% of mice develop squamous cell carcinomas at weeks 11 and 15, respectively, whereas wild-type mice develop similar percentages at weeks 16 and 20, respectively, following a daily dose of 250 J/m2
• yields of squamous cell carcinomas larger than 1mm and 2mm are increased following a daily dose of 250 J/m2

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory