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Phenotypes Associated with This Genotype
Genotype
MGI:3709976
Allelic
Composition		 Zfpm2tm1Sho/Zfpm2tm2Sho
Tg(Wap-cre)11738Mam/0
Genetic
Background		 involves: 129 * C57BL/6J * C57BL/6NCr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Wap-cre)11738Mam mutation (3 available)
Zfpm2tm1Sho mutation (2 available); any Zfpm2 mutation (45 available)
Zfpm2tm2Sho mutation (1 available); any Zfpm2 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:120985 )
N
• mice are fertile

endocrine/exocrine glands
abnormal mammary gland morphology ( J:120985 )
• at day 4 of involution, alveoli are completely collapsed into clusters of epithelial cells and the area containing adipocytes is greatly expanded
• however, after 6 days of involution there is no difference when compared to controls
abnormal involution of the mammary gland ( J:120985 )
• involution occurs faster at days 3 and 4 of involution than in controls

integument
abnormal mammary gland morphology ( J:120985 )
• at day 4 of involution, alveoli are completely collapsed into clusters of epithelial cells and the area containing adipocytes is greatly expanded
• however, after 6 days of involution there is no difference when compared to controls
abnormal involution of the mammary gland ( J:120985 )
• involution occurs faster at days 3 and 4 of involution than in controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory