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Phenotypes Associated with This Genotype
Genotype
MGI:3709890
Allelic
Composition
Tcf12tm1Zhu/Tcf12tm1Zhu
Genetic
Background
involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcf12tm1Zhu mutation (0 available); any Tcf12 mutation (64 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• thymocyte number is reduced 10-fold relative to controls in 2-3 week old mice
• block in development at the immature single positive (ISP) stage

hematopoietic system
• thymocyte number is reduced 10-fold relative to controls in 2-3 week old mice
• block in development at the immature single positive (ISP) stage

nervous system
N
• the pontine nucleus develops normally

endocrine/exocrine glands
• thymocyte number is reduced 10-fold relative to controls in 2-3 week old mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory