Phenotypes Associated with This Genotype

Genotype
MGI:3709862

• Allelic Composition: Runx1^tm2Spe/Runx1^tm3Spe; Tg(KRT5-cre)5132Jlj/0
• Genetic Background: either: (involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2J) or (involves: 129S4/SvJae * C57BL/6 * DBA/2J)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

increased curvature of auchene hairs ( J:116050 )

• majority of auchene hair type are altered in shape, many with more pronounced bends

abnormal coat appearance ( J:116050 )

• adult coat appears less dense and ruffled than controls

abnormal zigzag hair morphology ( J:116050 )

• about 90% of zigzag (ZZ) type hair show much less pronounced bends in 6-month old adults

• hair forms exhibit a variable number of bends compared to the three bend in control hairs; many do not have alternating bend patterns of control hairs, but have 2 bends in same direction

decreased curvature of zigzag hairs ( J:116050 )

• ~90% of zigzag (ZZ) type hair shows much less pronounced bends in 6-month old adults