Mouse Genome Informatics
cx
    Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-APPSwInd)102Dbo/0

involves: C3H/HeJ * C57BL/6 * CBA
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• mice produce transgenic APP protein at 10- to 30-fold over endogenous App levels
• suppression of transgene expression in these mice is most sensitive to doxycycline of the four lines tested

Mouse Models of Human Disease
OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:109829