Phenotypes Associated with This Genotype

Genotype
MGI:3709009

• Allelic Composition: repro46/repro46
• Genetic Background: B6;C3Fe-repro46/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

azoospermia ( J:92463 )

♂ • no sperm are recovered

arrest of male meiosis ( J:92463 )

♂ • arrest of germ cells during pachytene stage of meiotic prophase

decreased seminal vesicle weight ( J:92463 )

♂ • low seminal vesicle weight

small ovary ( J:92463 )

♀ • tiny ovaries with some follicle activity

hemorrhagic ovary cyst ( J:92463 )

♀ • hemorrhagic cysts present in some ovaries

abnormal seminiferous tubule morphology ( J:92463 )

♂ • some seminiferous tubules have only spermatogonia and Sertoli cells present

decreased testis weight ( J:92463 )

♂ • very low testis weight

female infertility ( J:92463 )

♀

male infertility ( J:92463 )

♂

endocrine/exocrine glands

decreased seminal vesicle weight ( J:92463 )

♂ • low seminal vesicle weight

small ovary ( J:92463 )

♀ • tiny ovaries with some follicle activity

hemorrhagic ovary cyst ( J:92463 )

♀ • hemorrhagic cysts present in some ovaries

abnormal seminiferous tubule morphology ( J:92463 )

♂ • some seminiferous tubules have only spermatogonia and Sertoli cells present

decreased testis weight ( J:92463 )

♂ • very low testis weight

growth/size/body

hemorrhagic ovary cyst ( J:92463 )

♀ • hemorrhagic cysts present in some ovaries

cellular

azoospermia ( J:92463 )

♂ • no sperm are recovered

arrest of male meiosis ( J:92463 )

♂ • arrest of germ cells during pachytene stage of meiotic prophase