Analysis Tools
reproductive system
| N |
• mice are fertile
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vision/eye
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• very thin
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• very thin
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• the overall structure of retina and number of photoreceptor cells is normal
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• retinal ganglion cells fail to differentiate as shown by the loss of Pou4f1+ and reduction of Ngfr+ cells
• approximately 97% of Pou4f2+ cells are lost
• 80% reduction in the SMI-32 positive processes of axons from large ganglion cells and the remaining 20% of SMI-32 positive processes of axons have abnormally curved axon bundles
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• greater than 80% reduction in the number of retinal ganglion cells
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• absence of a defined nerve fiber layer
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• retinas are approximately 15 to 20% thinner than control retinas
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nervous system
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• retinal ganglion cells fail to differentiate as shown by the loss of Pou4f1+ and reduction of Ngfr+ cells
• approximately 97% of Pou4f2+ cells are lost
• 80% reduction in the SMI-32 positive processes of axons from large ganglion cells and the remaining 20% of SMI-32 positive processes of axons have abnormally curved axon bundles
|
|
• greater than 80% reduction in the number of retinal ganglion cells
|
|
• very thin
|
|
• very thin
|
