Phenotypes Associated with This Genotype

Genotype
MGI:3707368

• Allelic Composition: Rims2^tm1.1Schc/Rims2^tm1.1Schc
• Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:119934 )

• at greater than 1 month of age, homozygotes are less frequent (19.1%) than expected (25%)

growth/size/body

decreased body size ( J:119934 )

• homozygous mice are slightly smaller than littermate controls (males)

behavior/neurological

abnormal maternal nurturing ( J:119934 )

♀ • females do not take care of their litters even after multiple pregnancies

nervous system

nervous system phenotype ( J:119934 )

N • mutants do not show differences in synaptic transmission, short-term synaptic plasticity, excitatory synapses in CA3, or inhibitory synaptic transmission at CA1 pyramidal cells compared to wild-type