Phenotypes for Hoxa1 Hoxb1 MGI:3703016 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hoxa1^{tm4(Hoxb1)Mrc}/Hoxa1^{tm4(Hoxb1)Mrc} Hoxb1^tm5Mrc/Hoxb1^{tm8(Hoxa1)Mrc}
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa1^{tm4(Hoxb1)Mrc} mutation (0 available); any Hoxa1 mutation (15 available)
Hoxb1^tm5Mrc mutation (0 available); any Hoxb1 mutation (24 available)
Hoxb1^{tm8(Hoxa1)Mrc} mutation (0 available); any Hoxb1 mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal reflex ( J:119279 )

• eyeblink reflex is impaired in 58% of mutants; only 11% are considered to be severely affected

nervous system

abnormal facial nerve morphology ( J:119279 )

• zygomatic and temporal branches of facial nerve have normal caliber, but occasionally show atypical arborization pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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