Phenotypes Associated with This Genotype

Genotype
MGI:3702901

• Allelic Composition: Igkc^tm1Bgmn/Igkc^tm1Bgmn; Igl^tm2Bgmn/Igl^tm2Bgmn
• Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

arrested B cell differentiation ( J:118712 )

• development is blocked at pre-B-II to immature B cell transition stage

absent B cells ( J:118712 )

• IgM+ B cells are undetectable in spleens of mutants

immune system

arrested B cell differentiation ( J:118712 )

• development is blocked at pre-B-II to immature B cell transition stage

absent B cells ( J:118712 )

• IgM+ B cells are undetectable in spleens of mutants