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Phenotypes Associated with This Genotype
Genotype
MGI:3702750
Allelic
Composition		 Prokr2tm1Brd/Prokr2tm1Brd
Genetic
Background		 B6.129S7-Prokr2tm1Brd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prokr2tm1Brd mutation (0 available); any Prokr2 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:119071 )
• on congenic background, the majority of homozygous mice do not survive to weaning age

growth/size/body
decreased body weight ( J:119071 )
• Background Sensitivity: on the congenic background, at 6 and 10 weeks of age, Prok2 homozygotes weigh significantly less (17 grams, 21 g respectively) than wild-type littermates (25 g, 29 g)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory