Phenotypes for Fgfr1 Spry2 MGI:3702559 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Fgfr1^tm1.1Jpa/Fgfr1⁺ Spry2^tm1.1Mrt/Spry2^tm1.1Mrt
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgfr1^tm1.1Jpa mutation (0 available); any Fgfr1 mutation (221 available)
Spry2^tm1.1Mrt mutation (1 available); any Spry2 mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

supernumerary teeth ( J:119280 )

• frequency of diastema tooth formation is reduced to 60% compared to almost 100% in mice homozygous for the Spry2 allele alone

growth/size/body

supernumerary teeth ( J:119280 )

• frequency of diastema tooth formation is reduced to 60% compared to almost 100% in mice homozygous for the Spry2 allele alone

skeleton

supernumerary teeth ( J:119280 )

• frequency of diastema tooth formation is reduced to 60% compared to almost 100% in mice homozygous for the Spry2 allele alone

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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