Phenotypes for Mesp1 Mesp2 MGI:3702332 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mesp1^tm3Ysa/Mesp1^tm3Ysa Mesp2^tm3(cre)Ysa/Mesp2^tm3(cre)Ysa
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mesp1^tm3Ysa mutation (1 available); any Mesp1 mutation (18 available)
Mesp2^tm3(cre)Ysa mutation (0 available); any Mesp2 mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:62984 )

• embryos exhibit a similar morphology and marker gene expression to Mesp1/Mesp2^tm1Ysa homozygous embryos, however no data is presented in J:62984

growth/size/body

abnormal embryonic growth/weight/body size ( J:62984 )

embryo

abnormal embryo development ( J:62984 )

cardiovascular system

abnormal heart morphology ( J:62984 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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