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Phenotypes Associated with This Genotype
Genotype
MGI:3702023
Allelic
Composition
Acacatm1Jkus/Acacatm1Jkus
Tg(Fabp1-cre)1Mmt/0
Genetic
Background
involves: 129X1/SvJ * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acacatm1Jkus mutation (0 available); any Acaca mutation (126 available)
Tg(Fabp1-cre)1Mmt mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• levels are slightly but significantly increased in males compared to wild-type at 9 weeks of age; these levels are still within normal range
• 10-week old males fed a high sucrose (67%) diet (HSD) for 3 days have slightly decreased de novo lipogenesis compared to controls on the HSD, but levels are 3-fold higher than controls fed a normal diet
• 10-week old males fed a high sucrose (67%) diet (HSD) for 3 days show ~70% decreased liver triglyceride levels than nontransgenic controls fed HSD

liver/biliary system
• 10-week old males fed a high sucrose (67%) diet (HSD) for 3 days show ~70% decreased liver triglyceride levels than nontransgenic controls fed HSD


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory