Phenotypes for C1qa Sle21 MGI:3701670 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	C1qa^tm1Mjw/C1qa^tm1Mjw Sle21^129P2/Ola/Sle21^C57BL/6
Genetic Background	involves: 129P2/Ola * 129S/SvEv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
C1qa^tm1Mjw mutation (1 available); any C1qa mutation (20 available)
Sle21^129P2/Ola mutation (0 available); any Sle21 mutation (0 available)
Sle21^C57BL/6 mutation (0 available); any Sle21 mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased susceptibility to systemic lupus erythematosus ( J:118645 )

increased anti-nuclear antigen antibody level ( J:118645 )

increased anti-chromatin antibody level ( J:118645 )

increased anti-double stranded DNA antibody level ( J:118645 )

increased anti-single stranded DNA antibody level ( J:118645 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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