Phenotypes Associated with This Genotype

Genotype
MGI:3700662

• Allelic Composition: Slc40a1^ffe/Slc40a1^ffe
• Genetic Background: involves: C3H/HeJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:118592 )

• mid-gestational lethality

hematopoietic system

anemia ( J:118592 )

• severe anemia

homeostasis/metabolism

edema ( J:118592 )

• Background Sensitivity: generalized edema is seen on a mixed background including C3H/HeJ but not in mice crossed onto 129X1/SvJ background

nervous system

abnormal neural tube closure ( J:118592 )

• Background Sensitivity: neural tube closure defects are seen on a mixed background including C3H/HeJ but not in mice crossed onto 129X1/SvJ background

abnormal forebrain development ( J:118592 )

• Background Sensitivity: forebrain truncations are seen on a mixed background including C3H/HeJ but not in mice crossed onto 129X1/SvJ background

vision/eye

microphthalmia ( J:118592 )

• Background Sensitivity: microphthalmia is seen on a mixed background including C3H/HeJ but not in mice crossed onto 129X1/SvJ background

embryo

abnormal neural tube closure ( J:118592 )

• Background Sensitivity: neural tube closure defects are seen on a mixed background including C3H/HeJ but not in mice crossed onto 129X1/SvJ background