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Phenotypes Associated with This Genotype
Genotype
MGI:3700374
Allelic
Composition		 Ikbkbtm2Cgn/Ikbkbtm2Cgn
Tg(Alb1-cre)7Gsc/0
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ikbkbtm2Cgn mutation (1 available); any Ikbkb mutation (56 available)
Tg(Alb1-cre)7Gsc mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal enzyme/coenzyme activity ( J:118336 )
• NF kappa b activation is completely blocked

liver/biliary system
liver/biliary system phenotype ( J:118336 )
N
• mice do not develop liver tumors or show liver steatosis in contrast to Ikbkg conditional mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory