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Phenotypes Associated with This Genotype
Genotype
MGI:3699811
Allelic
Composition		 Selptm1Bay/Selptm1Bay
Genetic
Background		 B6.129S7-Selptm1Bay/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Selptm1Bay mutation (3 available); any Selp mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell physiology ( J:113536 )
• T lymphocyte migration and accumulation into cutaneous inflammatory regions induced by a combination of IFN-gamma and TNF-alpha is inhibited by about 25%, however IFN-gamma, TNF-alpha, and ConA, has no effect on T cell infiltration

hematopoietic system
abnormal T cell physiology ( J:113536 )
• T lymphocyte migration and accumulation into cutaneous inflammatory regions induced by a combination of IFN-gamma and TNF-alpha is inhibited by about 25%, however IFN-gamma, TNF-alpha, and ConA, has no effect on T cell infiltration

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory