Phenotypes Associated with This Genotype

Genotype
MGI:3698425

• Allelic Composition: Rr100^tm2.1Welm/Rr100⁺
• Genetic Background: involves: 129P2/OlaHsd * AKR.1 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal T cell differentiation ( J:113136 )

• mice with one mutant Cd8a allele and a wild-type AKR.1 derived allele have ""CD8-negative"" single positive (SP) thymocytes expressing no CD8 alpha or beta

immune system

abnormal T cell differentiation ( J:113136 )

• mice with one mutant Cd8a allele and a wild-type AKR.1 derived allele have ""CD8-negative"" single positive (SP) thymocytes expressing no CD8 alpha or beta