Phenotypes Associated with This Genotype

Genotype
MGI:3698249

• Allelic Composition: Prrx1^tm1Tex/Prrx1^tm1Tex; Prrx2^tm1Hubr/Prrx2⁺
• Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

short Meckel's cartilage ( J:50488 )

• at E14.5, Meckel's cartilage is truncated

abnormal incisor morphology ( J:50488 )

• newborns exhibit closely spaced incisors

abnormal mandible morphology ( J:50488 )

• newborns exhibit shortened dentaries

skeleton

short Meckel's cartilage ( J:50488 )

• at E14.5, Meckel's cartilage is truncated

abnormal incisor morphology ( J:50488 )

• newborns exhibit closely spaced incisors

abnormal mandible morphology ( J:50488 )

• newborns exhibit shortened dentaries

abnormal metacarpal bone morphology ( J:50488 )

• the base of the metacarpal of the fifth digit is broader and forms an articulation with the trinagular and ulna

growth/size/body

abnormal incisor morphology ( J:50488 )

• newborns exhibit closely spaced incisors

abnormal mandible morphology ( J:50488 )

• newborns exhibit shortened dentaries

limbs/digits/tail

abnormal metacarpal bone morphology ( J:50488 )

• the base of the metacarpal of the fifth digit is broader and forms an articulation with the trinagular and ulna