Phenotypes Associated with This Genotype

Genotype
MGI:3698152

• Allelic Composition: Il2rg^tm1Krf/Il2rg^tm1Krf; Tg(Igh-Pim1)1Brn/0
• Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6 * CBA) or (involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased thymocyte number ( J:114561 )

♀ • thymocyte number is increased to 70-100 x 10⁶ cells compared to 10-25 x 10⁶ cells in null mice without the transgene but, the number is still decreased relative to wild-type mice (200-300 x 10⁶ cells)

hematopoietic system

decreased thymocyte number ( J:114561 )

♀ • thymocyte number is increased to 70-100 x 10⁶ cells compared to 10-25 x 10⁶ cells in null mice without the transgene but, the number is still decreased relative to wild-type mice (200-300 x 10⁶ cells)

endocrine/exocrine glands

decreased thymocyte number ( J:114561 )

♀ • thymocyte number is increased to 70-100 x 10⁶ cells compared to 10-25 x 10⁶ cells in null mice without the transgene but, the number is still decreased relative to wild-type mice (200-300 x 10⁶ cells)