Phenotypes Associated with This Genotype

Genotype
MGI:3696380

• Allelic Composition: Otx2^tm2(Otx1)Sia/Otx2⁺
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

craniofacial phenotype ( J:51989 )

N • craniofacial defects are largely restored by Otx1 expression; 86% are normal and none show acephaly

abnormal mandible morphology ( J:51989 )

• 3% have defects in the lower jaw

skeleton

abnormal mandible morphology ( J:51989 )

• 3% have defects in the lower jaw

vision/eye

abnormal eye morphology ( J:51989 )

• 3% have defects in the eyes