Mouse Genome Informatics
ht
    Satb2tm1(cre)Vit/Satb2+
involves: C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• fewer found at weaning than expected (about 35% compared to the expected 50%)

craniofacial
• at E11.5 a variable increase in apoptosis is seen in the mandibular BA1, maxillary BA1, and frontonasal mesenchyme regions that normally express Satb2
• seen in about 1/4 of mice
• variable incisor hypodontia and or adontia
• small
• strongly truncated and occasionally asymmetric

respiratory system

skeleton
• at E11.5 a variable increase in apoptosis is seen in the mandibular BA1, maxillary BA1, and frontonasal mesenchyme regions that normally express Satb2

digestive/alimentary system
• seen in about 1/4 of mice

growth/size/body
• seen in about 1/4 of mice
• variable incisor hypodontia and or adontia
• small
• strongly truncated and occasionally asymmetric
• slight

Mouse Models of Human Disease
OMIM IDRef(s)
Cleft Palate, Isolated; CPI 119540 J:116770