Phenotypes for Smad4 Tg(Pdx1-cre)89.1Dam MGI:3695419 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Smad4^tm1Rdp/Smad4^tm1Rdp Tg(Pdx1-cre)89.1Dam/0
Genetic Background	involves: 129S/SvEv * C57BL/6 * CBA * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smad4^tm1Rdp mutation (0 available); any Smad4 mutation (43 available)
Tg(Pdx1-cre)89.1Dam mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

digestive/alimentary system

duodenum polyps ( J:116130 )

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:116130 )

N	• pancreatic development, morphology, and function are all similar to wild-type and no pancreatic neoplasms develop

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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