Phenotypes Associated with This Genotype

Genotype
MGI:3694481

• Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor; Pdgfrb^tm3Sor/Pdgfrb^tm3Sor
• Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

midline facial cleft ( J:73817 )

• facial clefting

embryonic growth retardation ( J:73817 )

• a proportion display earlier embryonic defects such as growth retardation

embryo

incomplete embryo turning ( J:73817 )

• in most severe cases, fail to complete turning

embryonic growth retardation ( J:73817 )

• a proportion display earlier embryonic defects such as growth retardation

open neural tube ( J:73817 )

• in most severe cases, fail to complete the fusion of the neural folds by midgestation

failure of chorioallantoic fusion ( J:73817 )

• in most severe cases, fail to complete the fusion of chorion and allantois

craniofacial

midline facial cleft ( J:73817 )

• facial clefting

nervous system

open neural tube ( J:73817 )

• in most severe cases, fail to complete the fusion of the neural folds by midgestation

skeleton

rib fusion ( J:73817 )

integument

fetal bleb ( J:73817 )

• blebbing along the trunk of the embryo