Phenotypes for Six3 Tg(Pax6-cre,GFP)1Pgr MGI:3693847 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Six3^tm2Gco/Six3^tm2.1Gco Tg(Pax6-cre,GFP)1Pgr/0
Genetic Background	involves: 129S1/Sv * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Six3^tm2.1Gco mutation (0 available); any Six3 mutation (13 available)
Six3^tm2Gco mutation (0 available); any Six3 mutation (13 available)
Tg(Pax6-cre,GFP)1Pgr mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal forebrain development ( J:116102 )

• some embryos injected with tamoxifen early show defective forebrain patterning

vision/eye

abnormal lens induction ( J:116102 )

• when tamoxifen is given at E7.5 and 8.5, no thickening or invagination of the PLE is observed at least in one side

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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