nervous system
N |
• no Alzheimer's disease pathology is observed at 2 years of age in homozygotes
|
• homzygous mice have 4- to 6-fold higher levels of Abeta1-42 peptide in their brains compared to Tg(PSEN1H163R)G9Btla hemizygotes
|
homeostasis/metabolism
• homzygous mice have 4- to 6-fold higher levels of Abeta1-42 peptide in their brains compared to Tg(PSEN1H163R)G9Btla hemizygotes
|