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Phenotypes Associated with This Genotype
Genotype
MGI:3692749
Allelic
Composition		 A1cftm1Ddsn/A1cftm1Ddsn
Genetic
Background		 involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A1cftm1Ddsn mutation (1 available); any A1cf mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:114732 )
• embryos are detected at E3.5 but not at E4.5, indicating lethality by E4.5

cellular
decreased cell proliferation ( J:114732 )
• isolated blastocysts fail to proliferate in vitro

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory