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Phenotypes Associated with This Genotype
Genotype
MGI:3692742
Allelic
Composition		 Gfaptm3Mes/Gfaptm3Mes
Genetic
Background		 involves: 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gfaptm3Mes mutation (1 available); any Gfap mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:114689 )
• weigh less than wild-type or heterozygotes

nervous system
abnormal astrocyte morphology ( J:114689 )
• develop more Rosenthal fibers than heterozygotes

cellular
abnormal astrocyte morphology ( J:114689 )
• develop more Rosenthal fibers than heterozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory