Phenotypes Associated with This Genotype

Genotype
MGI:3692581

• Allelic Composition: Dmtf1^tm1Cjs/Dmtf1⁺
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased tumor incidence ( J:63444 , J:72617 )

• low but elevated tumor incidence in the first year (J:63444)

• wide variety of tumor types (J:63444)

• spontaneous lethal tumors develop with a high level of frequency in the second year of life, mean latency 83 weeks (J:72617)

increased incidence of induced tumors ( J:63444 )

• very susceptible to tumor induction by either ionizing radiation or dimethylbenzanthracene