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Phenotypes Associated with This Genotype
Genotype
MGI:3692550
Allelic
Composition
Rettm13.1Jmi/Rettm13.1Jmi
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rettm13.1Jmi mutation (1 available); any Ret mutation (53 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• midbrain dopaminergic neurons develop normally
• mice display intestinal aganglionosis

renal/urinary system
• renal agenesis occurs in homozygotes, identical to conventional Ret-null animals


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory