Phenotypes Associated with This Genotype

Genotype
MGI:3690880

• Allelic Composition: Cacna2d4^lob/Cacna2d4^lob
• Genetic Background: involves: A/J * C57BL/10

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal retina outer nuclear layer morphology ( J:112267 )

• about a 15% reduction in cell number, but no obvious change in the pattern or density of cones in the retina

thin retina outer plexiform layer ( J:112267 )

• significantly thinner

abnormal rod electrophysiology ( J:112267 )

• b wave and to a lesser extent a wave amplitudes are reduced

• a/b-wave ratio is about 25% that of wild-type mice