Phenotypes Associated with This Genotype

Genotype
MGI:3690647

• Allelic Composition: Kitl^Sl/Kitl⁺
• Genetic Background: involves: 129/Sv * C3H

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased tumor incidence ( J:50508 )

• male mice develop ~2-fold more tumors than controls

increased testicular teratoma incidence ( J:50508 )

♂ • incidence is 6.92% compared to ~2.6% in controls

♂ • tumors are predominantly in left testis (71%) vs right (27%) or bilateral (2%)

♂ • percentage is greater in second and subsequent litters compared to first litter or in first litter of older females compared to young mothers

reproductive system

increased testicular teratoma incidence ( J:50508 )

♂ • incidence is 6.92% compared to ~2.6% in controls

♂ • tumors are predominantly in left testis (71%) vs right (27%) or bilateral (2%)

♂ • percentage is greater in second and subsequent litters compared to first litter or in first litter of older females compared to young mothers

endocrine/exocrine glands

increased testicular teratoma incidence ( J:50508 )

♂ • incidence is 6.92% compared to ~2.6% in controls

♂ • tumors are predominantly in left testis (71%) vs right (27%) or bilateral (2%)

♂ • percentage is greater in second and subsequent litters compared to first litter or in first litter of older females compared to young mothers